Article
Computational and structural analysis of deleterious functional SNPs in ARNT oncogene.
Interdisciplinary sciences, computational life sciences - 1 Sept 2009
George Priya Doss C, Sethumadhavan Rao
Abstract excerpt
Along with the completion of human genome project, major interest in human genetics is to distinguish mutations that are functionally neutral from those that contribute to disease. The central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. The identification of such causal mutations not only provides insight into cancer biology but also presents anticancer...
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