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Ferroptosis in neurodegenerative diseases: mechanisms and therapeutic potential of stem cell derivatives

21 Mar 2025

Abstract excerpt

Ferroptosis, a non-apoptotic, iron-dependent form of regulated cell death, is closely related to the pathogenesis of neurodegenerative diseases. Stem cells and their derivatives exhibit remarkable potential in modulating ferroptosis, offering promising therapeutic intervention for neurodegenerative diseases. In this review, we systematically explore neurological aging and its association with cognitive impairment...

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PMID: 40191227
DOI: 10.3389/fcell.2025.1577382

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