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Article

Low-intensity pulsed ultrasound (LIPUS) switched macrophage into M2 phenotype and mitigated necroptosis and increased HSP 70 in gentamicin-induced nephrotoxicity.

Life sciences - 1 Feb 2023

Gouda Sarah Ali Abdelhameed, Aboulhoda Basma Emad, Abdelwahed Omaima Mohammed, Abdallah Hend, Rashed Laila, Hussein Rania Elsayed, Sharawy Nivin

Abstract excerpt

BACKGROUND AND AIM: Many attempts to control acute kidney injury (AKI) have failed due to a lack of understanding of its pathophysiological key components. Macrophages are a crucial determinant of AKI, which can be categorized functionally as M1 pro-inflammatory and M2 anti-inflammatory macrophages. Low-intensity pulsed ultrasound (LIPUS) is currently being investigated as an immune modulator. The present study...

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Identifiers

PMID: 36592788
DOI: 10.1016/j.lfs.2022.121338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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