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Article

An innovative single-base extension method for synchronous detection of point mutations and MSI status in colorectal cancer.

Cancer medicine - 1 Apr 2023

Liang Li, Li Xin, Nong Lin, Cai Weijing, Zhang Jixin, Liu Ping, Li Ting

Abstract excerpt

BACKGROUND: An accurate genotyping analysis is one of the critical prerequisites for patients with colorectal cancer receiving matched therapies. Conventional genotyping analysis is currently used to detect either gene mutations or MSI status, delaying the detection of critical tumor biomarkers and thus the optimal time for treatment. An assay that analyzes both biomarkers in a streamlined process is eagerly...

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PMID: 36583506
DOI: 10.1002/cam4.5557
PMCID: PMC10134345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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