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Article

MSIplus for Integrated Colorectal Cancer Molecular Testing by Next-Generation Sequencing.

The Journal of molecular diagnostics : JMD - 1 Nov 2015

Hempelmann Jennifer A, Scroggins Sheena M, Pritchard Colin C, Salipante Stephen J

Abstract excerpt

Molecular analysis of colon cancers currently requires multiphasic testing that uses various assays with different performance characteristics, adding cost and time to patient care. We have developed a single, next-generation sequencing assay to simultaneously evaluate colorectal cancers for mutations in relevant cancer genes (KRAS, NRAS, and BRAF) and for tumor microsatellite instability (MSI). In a sample set...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26322950
DOI: 10.1016/j.jmoldx.2015.05.008

Genes

BRAF
KRAS
NRAS

Provenance

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