Article
WebSTR: A Population-wide Database of Short Tandem Repeat Variation in Humans.
Journal of molecular biology - 15 Oct 2023
Lundström Oxana Sachenkova, Adriaan Verbiest Max, Xia Feifei, Jam Helyaneh Ziaei, Zlobec Inti, Anisimova Maria, Gymrek Melissa
Abstract excerpt
Short tandem repeats (STRs) are consecutive repetitions of one to six nucleotide motifs. They are hypervariable due to the high prevalence of repeat unit insertions or deletions primarily caused by polymerase slippage during replication. Genetic variation at STRs has been shown to influence a range of traits in humans, including gene expression, cancer risk, and autism. Until recently STRs have been poorly...
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