Article
Causal Effects of Plasma Proteome on Osteoporosis and Osteoarthritis.
Calcified tissue international - 1 Mar 2023
Han Bai-Xue, Yan Shan-Shan, Yu Han, Xu Qian, Zhao Qi-Gang, Ma Xin-Ling, Ni Jing-Jing, Zhang Lei, Pei Yu-Fang
Abstract excerpt
The two-sample Mendelian randomization (MR) study revealed a causal association of plasma proteins with osteoporosis (OP) and osteoarthritis (OA). Bone mineral density (BMD) is the gold standard for the clinical assessment of OP. Recent studies have shown that plasma proteins play an essential role in the regulation of bone development. However, the causal association of plasma proteins with BMD and OA remains...
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