Article
Pulmonary exacerbation inflammatory phenotypes in adults with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Mar 2023
Dong Kang, Huh Sung Moon, Lam Grace Y, Jang Jiah, Franciosi Alessandro N, Wilcox Pearce G, Quon Bradley S
Abstract excerpt
BACKGROUND: Adults with cystic fibrosis (CF) develop exuberant inflammatory responses during pulmonary exacerbations (PEx) but whether distinct systemic inflammatory profiles can be identified and whether these associate with disparate treatment outcomes are unclear. We conducted a pilot study to address this question and hypothesized that CF adults with a pauci-inflammatory phenotype might derive less clinical...
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