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Article

Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis.

The Journal of allergy and clinical immunology - 1 Jun 2014

Moore Wendy C, Hastie Annette T, Li Xingnan, Li Huashi, Busse William W, Jarjour Nizar N, Wenzel Sally E, Peters Stephen P, Meyers Deborah A, Bleecker Eugene R

Abstract excerpt

BACKGROUND: Clinical cluster analysis from the Severe Asthma Research Program (SARP) identified 5 asthma subphenotypes that represent the severity spectrum of early-onset allergic asthma, late-onset severe asthma, and severe asthma with chronic obstructive pulmonary disease characteristics. Analysis of induced sputum from a subset of SARP subjects showed 4 sputum inflammatory cellular patterns. Subjects with...

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Source

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Identifiers

PMID: 24332216
DOI: 10.1016/j.jaci.2013.10.011
PMCID: PMC4040309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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