Clinical and Inflammatory Phenotypes During Exacerbations Predict In-Hospital Adverse Outcomes in Asthma-COPD Overlap.

doi:10.1002/resp.70275

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinical and Inflammatory Phenotypes During Exacerbations Predict In-Hospital Adverse Outcomes in Asthma-COPD Overlap.

Respirology (Carlton, Vic.) - 1 Sept 2026

Yuan Lishan, Wang Lei, Yuan Yulai, Li Yilai, Zhang Li, Liu Ying, Liu Lei, Lu Lingyun, Feng Min, Wang Gang, Zhang Shuwen, Zhao Chongyang, Wang Qin, Kang Deying, Zhang Xin

Abstract excerpt

BACKGROUND AND OBJECTIVES: Exacerbations of asthma-chronic obstructive pulmonary disease overlap (EACO) are associated with high mortality, yet the acute-phase heterogeneity remains poorly characterized. This study aimed to identify distinct inflammatory phenotypes of EACO during hospitalization and evaluate their associations with clinical outcomes. METHODS: A prospective two-centre cohort study enrolled 2444...

Read the complete abstract on PubMed

Topics

Humans
Female
Male
Asthma
Phenotype
Prospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Pulmonary Disease, Chronic Obstructive

Disease Progression

Biomarkers

Aged

Neutrophils

Hospital Mortality

Eosinophils

Hospitalization

Inflammation

Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 42337860
DOI: 10.1002/resp.70275
PMCID: PMC13535756

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and Inflammatory Phenotypes During Exacerbations Predict In-Hospital Adverse Outcomes in Asthma-COPD Overlap.PMID 42337860Read ↗

Characterizing ECOPD Phenotypes: Associations with In-Hospital Outcomes and Immunoinflammatory Mechanisms.Semantic proximity Read ↗

Clinical Phenotypes of Patients Hospitalized for an Asthma Exacerbation: Prognostic Implications.Semantic proximity Read ↗

Clinical phenotyping and inflammatory biomarkers of asthma-COPD overlap: a cross-sectional, single-center study in China.Semantic proximity Read ↗

Common exacerbation-prone phenotypes across asthma and chronic obstructive pulmonary disease (COPD).Semantic proximity Read ↗

A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype.Semantic proximity Read ↗

Clinical phenotypes of asthma should link up with disease mechanisms.Semantic proximity Read ↗

Cluster Analysis of Inflammatory Biomarker Expression in the International Severe Asthma RegistrySemantic proximity Read ↗

Clinical and Inflammatory Features of Exacerbation-Prone Asthma: A Cross-Sectional Study Using Multidimensional Assessment.Semantic proximity Read ↗

From clinical phenotypes to cellular mechanisms: a precision medicine framework for COPD.Semantic proximity Read ↗

Effects of air pollution and meteorological factors on hematological exacerbation phenotypes in patients presenting to the emergency department with COPD exacerbation.Semantic proximity Read ↗

Clinical Assessment and Utility of Biomarkers in Asthma-Chronic Obstructive Pulmonary Disease Overlap.Semantic proximity Read ↗

Phenotypes, Etiotypes, and Endotypes of Exacerbations of Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.