Article
Acute Pulmonary Exacerbation Phenotypes in Patients with Cystic Fibrosis.
Annals of the American Thoracic Society - 1 Nov 2022
Carter Suzanne C, Franciosi Alessandro N, O'Shea Kate M, O'Carroll Orla M, Sharma Ashutosh, Bell Aoife, Keogan Brian, O'Reilly Paul, Coughlan Suzie, Law Sheonagh M, Gray Robert D, Hisert Katherine B, Singh Pradeep K, Cooke Gordon, Grogan Brenda, De Gascun Cillian F, Gallagher Charles G, Nicholson Trevor T, Quon Bradley S, McKone Edward F
Abstract excerpt
Rationale: The etiology of cystic fibrosis (CF) pulmonary exacerbations (PEx) is likely multifactorial with viral, bacterial, and non-infectious pathways contributing. Objectives: To determine whether viral infection status and CRP (C-reactive protein) can classify subphenotypes of PEx that differ in outcomes and biomarker profiles. Methods: Patients were recruited at time of admission for a PEx. Nasal swabs and...
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