Article
Role of transforming growth factor-beta superfamily signaling pathways in human disease.
Biochimica et biophysica acta - 1 Apr 2008
Gordon Kelly J, Blobe Gerard C
Abstract excerpt
Transforming growth factor beta (TGF-beta) superfamily signaling pathways are ubiquitous and essential regulators of cellular processes including proliferation, differentiation, migration, and survival, as well as physiological processes, including embryonic development, angiogenesis, and wound healing. Alterations in these pathways, including either germ-line or somatic mutations or alterations in the expression...
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