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The Emerging Role of uORF-Encoded uPeptides and HLA uLigands in Cellular and Tumor Biology

7 Dec 2022

Abstract excerpt

Recent technological advances have facilitated the detection of numerous non-canonical human peptides derived from regulatory regions of mRNAs, long non-coding RNAs, and other cryptic transcripts. In this review, we first give an overview of the classification of these novel peptides and summarize recent improvements in their annotation and detection by ribosome profiling, mass spectrometry, and individual...

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PMID: 36551517
DOI: 10.3390/cancers14246031

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