Article
Mechanisms of chromatin-based epigenetic inheritance.
Science China. Life sciences - 1 Nov 2022
Du Wenlong, Shi Guojun, Shan Chun-Min, Li Zhiming, Zhu Bing, Jia Songtao, Li Qing, Zhang Zhiguo
Abstract excerpt
Multi-cellular organisms such as humans contain hundreds of cell types that share the same genetic information (DNA sequences), and yet have different cellular traits and functions. While how genetic information is passed through generations has been extensively characterized, it remains largely obscure how epigenetic information encoded by chromatin regulates the passage of certain traits, gene expression states...
Topics
- Humans
- Chromatin
- Epigenesis, Genetic
- Inheritance Patterns
- Epigenomics
- Phenotype
- DNA Methylation
