Discovery of super-insecticide-resistant dengue mosquitoes in Asia: Threats of concomitant knockdown resistance mutations.

doi:10.1126/sciadv.abq7345

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Article

Discovery of super-insecticide-resistant dengue mosquitoes in Asia: Threats of concomitant knockdown resistance mutations.

Science advances - 21 Dec 2022

Kasai Shinji, Itokawa Kentaro, Uemura Nozomi, Takaoka Aki, Furutani Shogo, Maekawa Yoshihide, Kobayashi Daisuke, Imanishi-Kobayashi Nozomi, Amoa-Bosompem Michael, Murota Katsunori, Higa Yukiko, Kawada Hitoshi, Minakawa Noboru, Cuong Tran Chi, Yen Nguyen Thi, Phong Tran Vu, Keo Sath, Kang Kroesna, Miura Kozue, Ng Lee Ching, Teng Hwa-Jen, Dadzie Samuel, Subekti Sri, Mulyatno Kris Cahyo, Sawabe Kyoko, Tomita Takashi, Komagata Osamu

Abstract excerpt

Aedes aegypti (Linnaeus, 1762) is the main mosquito vector for dengue and other arboviral infectious diseases. Control of this important vector highly relies on the use of insecticides, especially pyrethroids. The high frequency (>78%) of the L982W substitution was detected at the target site of the pyrethroid insecticide, the voltage-gated sodium channel (Vgsc) of A. aegypti collected from Vietnam and Cambodia....

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Identifiers

PMID: 36542722
DOI: 10.1126/sciadv.abq7345
PMCID: PMC9770935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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