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Recent advances in the study of knockdown resistance mutations in Aedes mosquitoes with a focus on several remarkable mutations.

Current opinion in insect science - 1 Jun 2024

Uemura Nozomi, Itokawa Kentaro, Komagata Osamu, Kasai Shinji

Abstract excerpt

The Aedes mosquito, which transmits the dengue fever virus and other viruses, has acquired resistance to pyrethroid insecticides in a naturally selective manner. Massive use of insecticides has led to the worldwide expansion of resistant populations. The major factor in pyrethroid resistance is knockdown resistance (kdr) caused by amino acid mutation(s) in the voltage-gated sodium channel, which is the target...

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PMID: 38346494
DOI: 10.1016/j.cois.2024.101178

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