Article
Knockdown Resistance Mutations in Aedes aegypti (Diptera: Culicidae) From Puerto Rico.
Journal of medical entomology - 1 Nov 2016
Ponce-García Gustavo, Del Río-Galvan Samantha, Barrera Roberto, Saavedra-Rodriguez Karla, Villanueva-Segura Karina, Felix Gilberto, Amador Manuel, Flores Adriana E
Abstract excerpt
Permethrin resistance is widespread in Aedes aegypti (L.), the main dengue, zika, and chikungunya virus vector in Latin America and the Caribbean. A common mechanism of resistance to pyrethroids-knockdown resistance (kdr)-is conferred through mutations in the insect's voltage-dependent sodium channel. In this mosquito, around 10 replacement substitutions in the voltage-gated sodium channel gene (vgsc) have been...
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