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Article

Discovery of two novel mutations, R52H and N868D, in the voltage-gated sodium channel of Aedes aegypti associated with pyrethroid resistance.

PLoS neglected tropical diseases - 1 May 2026

Chung Han-Hsuan, Teng Hwa-Jen, Chen Shiu-Ling

Abstract excerpt

Aedes aegypti is the primary vector of arboviruses, including the dengue virus. Insecticide-based vector control remains a key strategy for reducing mosquito populations and disrupting disease transmission; however, its effectiveness is increasingly challenged by resistance. Identifying resistance mechanisms is crucial for monitoring resistance trends and informing policy decisions for vector control and disease...

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Identifiers

PMID: 42189875
DOI: 10.1371/journal.pntd.0014393
PMCID: PMC13225630

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