Article
Correlation between pyrethroid knockdown resistance and mutation frequency of voltage-gated sodium channel and its application in Aedes aegypti management.
Pesticide biochemistry and physiology - 1 Jan 2024
Lin Hsin-Hua, Li Zhong-Tai, Tzeng Hau-You, Chang Cheng, Dai Shu-Mei
Abstract excerpt
Aedes aegypti, the primary vector responsible for transmitting dengue fever in southern Taiwan, has developed a relatively high resistance to synthetic pyrethroids. It has evolved four amino acid substitutions in the voltage-gated sodium channel (VGSC), namely S996P, V1023G, F1565C, and D1794Y. To unveil the distribution and correlation of VGSC mutations and pyrethroid resistance among different field...
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