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Article

NPFFR2 gene compound heterozygous variants associated with preeclampsia identified by whole-exome sequencing.

Gene - 20 Feb 2023

Jiang Huling, Wang Luming, Zhu Jianjun, Ping Zepeng

Abstract excerpt

BACKGROUND: Preeclampsia (PE) is an idiopathic disorder of pregnancy. The exact cause of PE remains unknown. Emerging evidence indicates that the cause of PE is linked to genetic factors. Therefore, the aim of this study was to identify the susceptibility genes for PE. METHODS: Nine families with severe PE were recruited. The whole-exome sequencing (WES) was performed on each family, and Sanger sequencing was...

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PMID: 36535464
DOI: 10.1016/j.gene.2022.147108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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