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Article

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes

14 Jan 2019

Abstract excerpt

OBJECTIVE: Preeclampsia is a common and serious heritable disorder of human pregnancy. Although there have been notable successes in identification of maternal susceptibility genes a large proportion of the heritability of preeclampsia remains unaccounted for. It is has been postulated that rare variation may account for some of this missing heritability. In this study, we performed whole-exome sequencing (WES)...

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PMID: 30633125
DOI: 10.1097/hjh.0000000000002023

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