Article
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.
Human genetics - 1 Nov 2009
Johnson Matthew P, Roten Linda T, Dyer Thomas D, East Christine E, Forsmo Siri, Blangero John, Brennecke Shaun P, Austgulen Rigmor, Moses Eric K
Abstract excerpt
Preeclampsia is a heritable pregnancy disorder that presents new onset hypertension and proteinuria. We have previously reported genetic linkage to preeclampsia on chromosomes 2q, 5q and 13q in an Australian/New Zealand (Aust/NZ) familial cohort. This current study centered on identifying the susceptibility gene(s) at the 5q locus. We first prioritized candidate genes using a bioinformatic tool designed for this...
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