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Heterozygous FMN2 Missense Variant Found in A Family Case of Premature Ovarian Insufficiency

2021-09-08

Abstract excerpt

<title>Abstract</title> <p>Background Premature Ovarian Insufficiency plagues 1% of women under 40, while quite a few remain an unknown cause. The development of sequencing has helped find pathogenic genes and reveal the relationship between DNA repair and ovarian reserve. Through the exome sequencing, our study targets screening out the possible POI pathogenic gene and variants in a Chinese family and 20 sporad...

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Literature Corpus work: 83d73161-538c-5439-b2dc-efc2ed15e779
DOI: 10.21203/rs.3.rs-832452/v1

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