Article
The genetic component of preeclampsia: A whole-exome sequencing study.
PloS one - 1 Jan 2018
Hansen Anette Tarp, Bernth Jensen Jens Magnus, Hvas Anne-Mette, Christiansen Mette
Abstract excerpt
Preeclampsia is a major cause of maternal and perinatal deaths. The aetiology of preeclampsia is largely unknown but a polygenetic component is assumed. To explore this hypothesis, we performed an in-depth whole-exome sequencing study in women with (cases, N = 50) and without (controls, N = 50) preeclampsia. The women were identified in an unselected cohort of 2,545 pregnant women based on data from the Danish...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.