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Network medicine informed multi-omics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis

2024-03-30

Abstract excerpt

Amyotrophic Lateral Sclerosis (ALS) is a devastating, immensely complex neurodegenerative disease by lack of effective treatments. To date, the challenge to establishing effective treatment for ALS remains formidable, partly due to inadequate translation of existing human genetic findings into actionable ALS-specific pathobiology for subsequent therapeutic development. This study evaluates the feasibility of netwo...

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Literature Corpus work
e277cd17-35c3-566c-a99f-8b09f1978bb2
DOI
10.1101/2024.03.27.586949
Open publication

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Network medicine informed multi-omics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral SclerosisDOI 10.1101/2024.03.27.586949
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