Article
The spectrum of tuberculosis described as differential DNA methylation patterns in alveolar macrophages and alveolar T cells
1 Dec 2022
Abstract excerpt
BACKGROUND: Host innate immune cells have been identified as key players in the early eradication of Mycobacterium tuberculosis and in the maintenance of an anti-mycobacterial immune memory, which we and others have shown are induced through epigenetic reprogramming. Studies on human tuberculosis immunity are dominated by those using peripheral blood as surrogate markers for immunity. We aimed to investigate DNA...
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