Article

Hyd ubiquitinates the NF-κB co-factor Akirin to activate an effective immune response in <i>Drosophila</i>

2018-05-16

Abstract excerpt

<h4>One Sentence Summary</h4> Upon microbial infection in Drosophila , the E3-ubiquitin ligase Hyd ubiquitinylates the NF-κB co-factor Akirin for its efficient binding to the NF-κB factor Relish and subsequent activation of immune effectors genes. <h4>ABSTRACT</h4> The Drosophila IMD pathway is activated upon microbial challenge with Gramnegative bacteria to trigger the innate immune response. In order to dec...

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Literature Corpus work: 22917a4f-0334-50e6-97bb-3d70eaf1176e
DOI: 10.1101/323170

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