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Article

[18F]RO948 tau positron emission tomography in genetic and sporadic frontotemporal dementia syndromes.

European journal of nuclear medicine and molecular imaging - 1 Apr 2023

Santillo Alexander F, Leuzy Antoine, Honer Michael, Landqvist Waldö Maria, Tideman Pontus, Harper Luke, Ohlsson Tomas, Moes Svenja, Giannini Lucia, Jögi Jonas, Groot Colin, Ossenkoppele Rik, Strandberg Olof, van Swieten John, Smith Ruben, Hansson Oskar

Abstract excerpt

PURPOSE: To examine [18F]RO948 retention in FTD, sampling the underlying protein pathology heterogeneity. METHODS: A total of 61 individuals with FTD (n = 35), matched cases of AD (n = 13) and Aβ-negative cognitively unimpaired individuals (n = 13) underwent [18F]RO948PET and MRI. FTD included 21 behavioral variant FTD (bvFTD) cases, 11 symptomatic C9orf72 mutation carriers, one patient with non-genetic...

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Identifiers

PMID: 36513817
DOI: 10.1007/s00259-022-06065-4
PMCID: PMC10027632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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