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Article

18F-MK-6240 tau-PET in genetic frontotemporal dementia.

Brain : a journal of neurology - 3 Jun 2022

Levy Jake P, Bezgin Gleb, Savard Melissa, Pascoal Tharick A, Finger Elizabeth, Laforce Robert, Sonnen Joshua A, Soucy Jean-Paul, Gauthier Serge, Rosa-Neto Pedro, Ducharme Simon

Abstract excerpt

Tau is one of several proteins associated with frontotemporal dementia. While knowing which protein is causing a patient's disease is crucial, no biomarker currently exists for identifying tau in vivo in frontotemporal dementia. The objective of this study was to investigate the potential for the promising 18F-MK-6240 PET tracer to bind to tau in vivo in genetic frontotemporal dementia. We enrolled subjects with...

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Identifiers

PMID: 34664612
DOI: 10.1093/brain/awab392
PMCID: PMC9166561

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