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An open dataset of cerebral tau deposition in young healthy adults based on [ <sup>18</sup> F]MK6240 positron emission tomography

2025-06-14

Abstract excerpt

Tauopathies are pathologies wherein phosphorylated insoluble tau aggregates in neurons, leading to dysfunction and degeneration. Positron emission tomography (PET) enables measurement of in vivo tau, with second-generation radiotracers such as [ 18 F]MK6240 showing high tau affinity with minimal off-target binding. While tauopathies are commonly linked to age-related neurodegenerative diseases, notably Alzheimer...

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Literature Corpus work
79de1869-14a2-53ff-92e9-ed8cb1a6e8e8
DOI
10.1101/2025.06.13.655622
Open publication

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