Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The collective effects of genetic variants and complex traits.

Journal of human genetics - 1 Apr 2023

Wang Mingrui, Huang Shi

Abstract excerpt

Traditional approaches in studying the genetics of complex traits have focused on identifying specific genetic variants. However, the collective effects of variants have remained largely unexplored. Here, we evaluated whether traits could be influenced by the collective effects of variants across the entire protein coding-region of the genome or the entire genome. We studied the UK Biobank exome sequencing data...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exome
Share to Exome Sequencing
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36513763
DOI: 10.1038/s10038-022-01105-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The collective effects of genetic variants and complex traits.PMID 36513763Read ↗

Genetic and molecular architecture of complex traits.Semantic proximity Read ↗

Human genetic variation and its contribution to complex traits.Semantic proximity Read ↗

Phenome-wide Heritability Analysis of the UK BiobankSemantic proximity Read ↗

Distinct genetic architecture in the tails of complex traits.Semantic proximity Read ↗

Genetic architecture: the shape of the genetic contribution to human traits and disease.Semantic proximity Read ↗

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.Semantic proximity Read ↗

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.Semantic proximity Read ↗

The fog of genetics: Known unknowns and unknown unknowns in the genetics of complex traits and diseasesSemantic proximity Read ↗

Genetics of complex traits in psychiatry.Semantic proximity Read ↗

Common and rare alleles as causes of complex phenotypes.Semantic proximity Read ↗

Common genetic variants contribute to risk of rare severe neurodevelopmental disordersSemantic proximity Read ↗

Genetic architecture of complex traits and disease risk predictors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.