Article
Family-based association analysis between nonsyndromic cleft lip with or without cleft palate and IRF6 polymorphism in an Iranian population.
Clinical oral investigations - 1 May 2015
Nouri Nayereh, Memarzadeh Mehrdad, Carinci Francesco, Cura Francesca, Scapoli Luca, Nouri Narges, Jafary Fariba, Sedghi Maryam, Sadri Leyli, Salehi Mansoor
Abstract excerpt
OBJECTIVES: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect which is strongly associated with genetic factors. Previous studies in several populations showed a significant correlation between IRF6 rs642961 polymorphism and NSCL/P. The aim of this study is to indicate the correlation of IRF6 rs642961 polymorphism and NSCL/P in Iranian NSCL/P families. MATERIAL AND METHODS: In...
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