Article
Establishment and characterization of urothelial carcinoma cell lines with and without BRAF mutation (V595E) in dogs.
In vitro cellular & developmental biology. Animal - 1 Dec 2022
Yamasaki Hirofumi, Uematsu Yosuke, Okano Kumiko, Ichikawa Mika, Tei Meina, Hirabayashi Miyuki, Uchida Kazuyuki, Ono Kenichiro, Hirao Hidehiro
Abstract excerpt
Each 5 urothelial carcinoma (UC) cell lines with and without the v-Raf murine sarcoma virus oncogene homolog B (BRAF) gene mutation (V595E) were established and examined V595E-related tumorigenic characteristics in dogs. No typical morphological features were observed in cloned cells with and without V595E. The cell proliferation of both cloned cells showed logarithmic growth curve and those doubling time were...
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