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Article

Dendritic cells direct circadian anti-tumour immune responses

5 Dec 2022

Abstract excerpt

Abstract The process of cancer immunosurveillance is a mechanism of tumour suppression that can protect the host from cancer development throughout its lifetime 1,2 . However, it is unknown whether the effectiveness of cancer immunosurveillance fluctuates over a single day. Here we demonstrate that the initial time of day of tumour engraftment dictates the ensuing tumour size across mouse cancer models. Using...

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PMID: 36470303
DOI: 10.1038/s41586-022-05605-0

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