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WITHDRAWN: Circadian Clock-Gene Structure Couples with PD-L1 Across Six Cancer Types and Defines Survival-Associated Subtypes in Melanoma

2026-02-18

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<title>Abstract</title> <p>Background. Circadian disruption is classified by IARC as a probable human carcinogen (Group 2A). The relationship between clock-gene expression structure and immune checkpoint engagement across cancer types is poorly characterized. We hypothesized that circadian program state and PD-L1 engagement are coupled, reflecting distinct modes of immune evasion. Methods. We analyzed bulk RNA-...

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Literature Corpus work
6bf7dfcb-d4a3-5469-82d1-57ac1449098d
DOI
10.21203/rs.3.rs-8885012/v1
Open publication

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WITHDRAWN: Circadian Clock-Gene Structure Couples with PD-L1 Across Six Cancer Types and Defines Survival-Associated Subtypes in MelanomaDOI 10.21203/rs.3.rs-8885012/v1
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