Article
[Tumor progression of diffuse median glioma with H3 K27 alteration from pilocytic astrocytoma to glioblastoma].
Arkhiv patologii - 1 Jan 2022
Zabrodskaya Yu M, Sidorin V S, Nikolaenko M S, Samochernikh K A
Abstract excerpt
In the latest revisions of the WHO Classification of CNS Tumors, carried out in 2016 and 2021, the traditional histogenetic classification of gliomas is rebuilt on a new molecular genetic basis, according to which diffuse midline glioma with alteration of histone H3 K27 is distinguished as a specific pediatric oncosyndrome. The rationale was the association of this feature of midline gliomas in children with a...
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