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Genetic analysis of activin/inhibin β subunits in zebrafish development and reproduction

5 Dec 2022

Abstract excerpt

Activin and inhibin are both dimeric proteins sharing the same β subunits that belong to the TGF-β superfamily. They are well known for stimulating and inhibiting pituitary FSH secretion, respectively, in mammals. In addition, activin also acts as a mesoderm-inducing factor in frogs. However, their functions in development and reproduction of other species are poorly defined. In this study, we disrupted all three...

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PMID: 36469526
DOI: 10.1371/journal.pgen.1010523

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