Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.

doi:10.1101/gad.8.4.414

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Article

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.

Genes & development - 15 Feb 1994

Vassalli A, Matzuk M M, Gardner H A, Lee K F, Jaenisch R

Abstract excerpt

Inhibins and activins are dimeric growth factors of the transforming growth factor-beta superfamily, a class of peptides that can regulate the growth and differentiation of a variety of cell types. Recently, activins have been implicated in early vertebrate development through their ability to evoke, in Xenopus embryo explants, both morphological and molecular changes characteristic of mesoderm induction. To...

Topics

Activins
Animals
Base Sequence
DNA Probes
Embryonic and Fetal Development
Eyelids
Female
Inhibins
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Mutant Strains

Molecular Sequence Data

Ovary

Phenotype

Pregnancy

Protein Conformation

Source

Open in PubMed

Identifiers

PMID: 8125256
DOI: 10.1101/gad.8.4.414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8125256-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction.PMID 8125256Read ↗

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