Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted gene disruption in zebrafish reveals noncanonical functions of LH signaling in reproduction.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2014

Chu Lianhe, Li Jianzhen, Liu Yun, Hu Wei, Cheng Christopher H K

Abstract excerpt

The pivotal role of gonadotropin signaling in regulating gonadal development and functions has attracted much research attention in the past 2 decades. However, the precise physiological role of gonadotropin signaling is still largely unknown in fish. In this study, we have established both LH β-subunit (lhb) and LH receptor (lhr) knockout zebrafish lines by transcription activator-like effector nucleases....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fertilization
Share to Ovarian Follicle
Share to Ovulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, FSH

Share to Receptors, LH

Share to Sperm Motility

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25238195
DOI: 10.1210/me.2014-1061
PMCID: PMC5414790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted gene disruption in zebrafish reveals noncanonical functions of LH signaling in reproduction.PMID 25238195Read ↗

Gonadotropin Signaling in Zebrafish Ovary and Testis Development: Insights From Gene Knockout StudySemantic proximity Read ↗

Disruption of Zebrafish Follicle-Stimulating Hormone Receptor (fshr) But Not Luteinizing Hormone Receptor (lhcgr) Gene by TALEN Leads to Failed Follicle Activation in Females Followed by Sexual Reversal to Males.Semantic proximity Read ↗

Roles of Gonadotropin Receptors in Sexual Development of MedakaSemantic proximity Read ↗

The highly overlapping actions of Lh signaling and Fsh signaling on zebrafish spermatogenesisSemantic proximity Read ↗

Loss of follicle-stimulating hormone receptor function causes masculinization and suppression of ovarian development in genetically female medaka.Semantic proximity Read ↗

Nuclear Progestin Receptor (Pgr) Knockouts in Zebrafish Demonstrate Role for Pgr in Ovulation but Not in Rapid Non-Genomic Steroid Mediated Meiosis ResumptionSemantic proximity Read ↗

Genetic analysis of activin/inhibin β subunits in zebrafish development and reproductionSemantic proximity Read ↗

Evolution of the Hypothalamic-Pituitary-Gonadal Axis Regulation in Vertebrates Revealed by Knockout MedakaSemantic proximity Read ↗

Genetic evidence for Amh modulation of gonadotropin actions to control gonadal homeostasis and gametogenesis in zebrafish and its noncanonical signalling through Bmpr2a receptorSemantic proximity Read ↗

The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females.Semantic proximity Read ↗

What have we learned about gonadotropin function from gonadotropin subunit and receptor knockout mice?Semantic proximity Read ↗

The luteinizing hormone receptor knock-out mouse as a tool to probe the <i>in vivo</i> actions of gonadotropic hormones/receptors in femalesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.