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Article

Functional landscape of zebrafish gonadotropins and receptors: a comprehensive genetic analysis.

Genetics - 2 Sept 2026

Zeng Chu, Zhang Zhiwei, Zhou Lingling, Zhou Xianqing, Ai Nana, Ge Wei

Abstract excerpt

In vertebrates, reproduction is primarily controlled by two master hormones, or gonadotropins, from the pituitary: follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act through their cognate receptors, FSHR and LHCGR, in gonads. Like other vertebrates, zebrafish also has two gonadotropins and respective receptors. However, while zebrafish FSH activates Fshr specifically, its LH can activate...

Read the complete abstract on PubMed

Topics

Animals
Zebrafish
Receptors, FSH
Female
Zebrafish Proteins
Signal Transduction
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Receptors, LH

Luteinizing Hormone

Follicle Stimulating Hormone

Gonadotropins

Mutation

Reproduction

Source

Identifiers

PMID: 42376857
DOI: 10.1093/genetics/iyag169

Genes

FSHR
LHCGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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