Article
A kidney resident macrophage subset is a candidate biomarker for renal cystic disease in preclinical models
2 Dec 2022
Abstract excerpt
Although renal macrophages have been shown to contribute to cyst development in polycystic kidney disease (PKD) animal models, it remains unclear whether there is a specific macrophage subpopulation involved. Here, we analyzed changes in macrophage populations during renal maturation in association with cystogenesis rates in conditional Pkd2 mutant mice. We observed that CD206+ resident macrophages were minimal...
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