Article
Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2023
Batdorj Enkhjin, AlOgayil Najla, Zhuang Qinwei Kim-Wee, Galvez Jose Hector, Bauermeister Klara, Nagata Kei, Kimura Tohru, Ward Monika A, Taketo Teruko, Bourque Guillaume, Naumova Anna K
Abstract excerpt
Several lines of evidence suggest that the presence of the Y chromosome influences DNA methylation of autosomal loci. To better understand the impact of the Y chromosome on autosomal DNA methylation patterns and its contribution to sex bias in methylation, we identified Y chromosome dependent differentially methylated regions (yDMRs) using whole-genome bisulfite sequencing methylation data from livers of mice...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
