Article
DMY is a Y-specific DM-domain gene required for male development in the medaka fish.
Nature - 30 May 2002
Matsuda Masaru, Nagahama Yoshitaka, Shinomiya Ai, Sato Tadashi, Matsuda Chika, Kobayashi Tohru, Morrey Craig E, Shibata Naoki, Asakawa Shuichi, Shimizu Nobuyoshi, Hori Hiroshi, Hamaguchi Satoshi, Sakaizumi Mitsuru
Abstract excerpt
Although the sex-determining gene Sry has been identified in mammals, no comparable genes have been found in non-mammalian vertebrates. Here, we used recombinant breakpoint analysis to restrict the sex-determining region in medaka fish (Oryzias latipes) to a 530-kilobase (kb) stretch of the Y chromosome. Deletion analysis of the Y chromosome of a congenic XY female further shortened the region to 250 kb. Shotgun...
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