Article
Sex Chromosomes and Sex Phenotype Contribute to Biased DNA Methylation in Mouse Liver.
Cells - 9 Jun 2020
Zhuang Qinwei Kim-Wee, Galvez Jose Hector, Xiao Qian, AlOgayil Najla, Hyacinthe Jeffrey, Taketo Teruko, Bourque Guillaume, Naumova Anna K
Abstract excerpt
Sex biases in the genome-wide distribution of DNA methylation and gene expression levels are some of the manifestations of sexual dimorphism in mammals. To advance our understanding of the mechanisms that contribute to sex biases in DNA methylation and gene expression, we conducted whole genome bisulfite sequencing (WGBS) as well as RNA-seq on liver samples from mice with different combinations of sex phenotype...
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