Article
The Role of the Immune Phenotype in Tumor Progression and Prognosis of Patients with Mycosis Fungoides: A Quantitative Immunohistology Whole Slide Approach.
Cells - 11 Nov 2022
Aulasevich Natallia, Haist Maximilian, Försch Sebastian, Weidenthaler-Barth Beate, Mailänder Volker
Abstract excerpt
BACKGROUND AND OBJECTIVES: Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphomas, characterized by mature, skin-tropic CD4+ T-helper cells. In order to study the immune tumor microenvironment in MF patients, we performed immunohistochemical stains on MF biopsies, digitized whole-slide tissue sections, and performed quantitative analysis of the different immune cell subsets to correlate...
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