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Somatic mutations in tumor and plasma of locoregional recurrent and/or metastatic head and neck cancer using a next-generation sequencing panel: A preliminary study.

Cancer medicine - 1 Mar 2023

Rapado-González Óscar, Brea-Iglesias Jenifer, Rodríguez-Casanova Aitor, Bao-Caamano Aida, López-Cedrún José-Luis, Triana-Martínez Gabriel, Díaz-Peña Roberto, Santos María Arminda, López-López Rafael, Muinelo-Romay Laura, Martínez-Fernández Mónica, Díaz-Lagares Ángel, Suárez-Cunqueiro María Mercedes

Abstract excerpt

BACKGROUND: We explore the utility of TruSight Tumor 170 panel (TST170) for detecting somatic mutations in tumor and cfDNA from locoregional recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC). METHODS: Targeted NGS of tumor DNA and plasma cfDNA was performed using TST170 panel. In addition, a set of somatic mutations previously described in HNSCC were selected for validating in tumor,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36420687
DOI: 10.1002/cam4.5436
PMCID: PMC10067107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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