Article
A comparison between mutational profiles in tumour tissue DNA and circulating tumour DNA in head and neck squamous cell carcinoma - A systematic review.
Mutation research. Reviews in mutation research - 1 Jan 2000
Huang Xiaomin, Leo Paul, Jones Lee, Duijf Pascal H G, Hartel Gunter, Kenny Lizbeth, Vasani Sarju, Punyadeera Chamindie
Abstract excerpt
BACKGROUND: Head and neck cancer is the seventh most common malignancy globally. Head and neck squamous cell carcinoma (HNSCC) originates from squamous cells and 90% of HNC are HNSCC. The gold standard for diagnosing HNSCC is tissue biopsy. However, given tumour heterogeneity, biopsies may miss important cancer-associated molecular signatures, and more importantly, after the tumour is excised, there is no means...
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