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Article

Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction

17 Oct 2022

Abstract excerpt

Transmission of SARS-CoV-2 from humans to other species threatens wildlife conservation and may create novel sources of viral diversity for future zoonotic transmission. A variety of computational heuristics have been developed to pre-emptively identify susceptible host species based on variation in the angiotensin-converting enzyme 2 (ACE2) receptor used for viral entry. However, the predictive performance of...

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PMID: 36416537
DOI: 10.7554/elife.80329

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