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SLIT2 promoter hypermethylation predicts disease progression in chronic myeloid leukemia

21 Nov 2022

Abstract excerpt

BACKGROUND: Aberrant DNA methylation plays a crucial role in the progression of myeloid neoplasms. Previously, our literature reported that slit guidance ligand 2 (SLIT2) promoter methylation was associated with disease progression and indicated a poor prognosis in patients with myelodysplastic syndrome. Herein, we further investigated the clinical implications and role of SLIT2 promoter methylation in patients...

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Share to Chronic Myeloid Leukemia Treatments
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PMID: 36411451
DOI: 10.1186/s40001-022-00899-2

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