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Article

Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms

1 Jun 2020

Abstract excerpt

The deregulated DLX gene family members DLX1/2/3/4/5/6 (DLXs) caused by DNA methylation has been demonstrated in various cancers with therapeutic target value. However, the potential role of DLXs methylation in myeloid neoplasms such as acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) remains to be elucidated. Clinical significance of DLXs methylation/expression was analyzed in patient with AML...

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PMID: 32508046
DOI: 10.1002/ctm2.29

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